Cultured meat startup Prolific Machines unveils its ‘Henry Ford strategy’ to cell development


The global cultured meat market is poised to succeed in half a billion {dollars} by 2030; nonetheless, this sort of know-how remains to be very a lot within the R&D part for lots of corporations which have emerged over the previous 5 years.

Cultured meat, often known as cultivated meat, is animal meat, however as an alternative of slaughtering the animal to get it, cells are collected from the animal and cultivated in a lab the place they’re then assembled right into a construction of tissue that resembles the identical meat all of us eat.

We’ve seen a couple of cultured meat corporations unveil their merchandise. For instance, Novel Farms has a pork loin, whereas Bluu Seafood, a German firm growing lab-grown seafood, debuted its fish sticks and fish balls final month. Similar for Dutch-based Meatable with its sausages, SCiFi Foods with its burgers, and rooster for UPSIDE Foods.

Nonetheless, the manufacturing course of for aesthetic meat has traditionally been “each very troublesome and really costly,” Prolific Machines’ co-founder and CEO Deniz Kent informed TechCrunch. That’s what his firm is out to vary.

“You must use these development media proteins that are a number of the most costly issues — one of many proteins we’re changing is like 30,000 occasions costlier than a gram of gold,” he added. “It’s actually exhausting to scale something because of this as a result of it’s important to use these proteins.”

Kent, who has experience in stem cell biology, defined that these proteins have been used for many years, primarily within the biopharmaceutical trade. The know-how works on pharmaceutical merchandise which have massive budgets, however not so good when you’re attempting to make a high-volume, low-margin product like meat, he added.

Whereas having the concept for higher proteins, he met physicist Max Huisman and machine studying engineer Declan Jones and satisfied them to give up their jobs and type Prolific Machines with him in 2020.

That stated, Prolific Machines believes it has a novel manufacturing strategy for aesthetic meat cells and is popping out of stealth mode with $42 million in mixed seed and Collection A funding to construct what Kent calls an “meeting line for biology.”

The corporate goals to do for biology what Henry Ford did for vehicles on the flip of the twentieth century. Its know-how, nonetheless in its early phases, is a method to develop and management cells with out the necessity for any of these costly recombinant proteins for cell manufacturing, he stated. Prolific Machines will carry merchandise to market, however can even license its infrastructure to different cultured meat corporations.

“Again then, no person actually owned vehicles other than super-rich folks. What actually modified issues was Ford,” Kent stated. “They constructed the meeting line for vehicles and located a method to manufacture vehicles at a value that standard folks might afford. That reworked the trade as a result of you then went from a whole bunch of automobile corporations to solely three corporations having over 70% of the market.”

He believes the identical factor goes to occur within the cultured meat trade: There are a whole bunch of corporations proper now, however “most of them will die as a result of they gained’t have a method to manufacture cultured meat low cost sufficient. Those that may discover a approach will survive,” he added.

Prolific Machines was a part of SOSV’s IndieBio program in 2021. SOSV led Prolific Machines’ pre-seed spherical. In the meantime, for its new capital infusion, the seed-round portion was led by Arvind Gupta, associate at Mayfield, and the Collection A by Invoice Gates–based Breakthrough Vitality Ventures.

“I by no means supposed to spend money on one other cultured meat firm, however when Deniz confirmed me what they have been doing, I used to be blown away by the creativity of their strategy to reinvent the meeting line for meals manufacturing,” Gupta stated in a written assertion. “It’s my objective to assist reverse local weather change by partnering with unimaginable groups, and I’m satisfied Prolific Machines will probably be a winner within the race for sustainable meals manufacturing.”

Becoming a member of in on the 2 rounds was a gaggle of VC corporations and particular person buyers, together with David Adelman, Mark Cuban, The Kraft Household, David Rubenstein, Michael Rubin, Breyer Capital, The SALT Fund, Purple Orange Ventures, Fred Blackford, Jake Poliskin, Matt Katz and Baruch Future Ventures. Add to {that a} group of celebrities and restaurateurs, together with Kevin Love, Tobias Harris, Meek Mill, Ciara and Russell Wilson, Emily Ratajkowski, Maverick Carter, Sean Feeney, Michael Schulson, Mark Bucher and RJ Melman.

Kent stated the Collection A was raised a yr in the past, however the firm is popping out of stealth now because it prepares to boost a fairly hefty “$170 million-ish” Collection B within the first quarter of 2023. The brand new funding will go towards constructing a 25,000-square-foot headquarters in Emeryville, California, and ramp up hiring to broaden its meeting line packages, together with fish, poultry and beef.

In the meantime, he expects the power to be completed in spring 2023. Plans for the corporate’s first product embody an unstructured Wagyu, which implies floor meat. Prolific Machines additionally has plenty of high-profile cooks — none that Kent might title now — who’ve agreed to associate with the corporate and use its first cultured meat merchandise.



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