Andreessen Horowitz backs Synonym’s bio-manufacturing services • TechCrunch

Armed with $6.3 million in new pre-seed capital, Synonym Biotechnologies has begun the event part for its first productized bio-manufacturing services for non-pharmaceutical functions.

Edward Shenderovich and Joshua Lachter began the corporate in January 2022 to develop, finance and construct commercial-scale bio-manufacturing services to offer artificial biology producers of all measurement with versatile manufacturing capability whereas additionally giving infrastructure buyers entry to a brand new, carbon-negative bio-manufacturing asset class they’re calling “fermentation farms.”

Andreessen Horowitz, Large Ventures, Blue Horizon, Thia Ventures and different enterprise funds energetic in decarbonization had been a part of the funding.

Shenderovich and Lachter closed on the funding this month and informed TechCrunch through electronic mail that the pre-seed spherical “has allowed us to construct an distinctive and well-rounded launch crew and set up our product available in the market.”

“We plan to make use of the capital to catalyze our facility improvement efforts,” CEO Shenderovich mentioned. “This implies specializing in hiring throughout our design, engineering and finance groups to put the foundations for our first facility break-ground and speed up our outreach for strategic partnerships throughout the worth chain.”

Synonym is growing each the standardized designs and underwriting requirements for financing its fermentation farms in order that firms will be capable of simply make the most of them to provide higher high quality bioproducts at decrease prices than current choices. On the investor facet, the corporate mentioned it’s constructing an underwriting mannequin to offer ESG funding alternatives.

The corporate can also be channeling the U.S. authorities’s current executive order on bio-manufacturing that wishes to speed up innovation on this space to satisfy targets round local weather and vitality targets, meals safety and sustainability and provide chains.

Nevertheless, Shenderovich and Lachter say this can solely be potential if bioproducts, for instance, dairy protein, polymers and resins, attain price parity to legacy merchandise.

And proper now, the infrastructure to correctly scale “doesn’t exist immediately” in a means that permits firms to make the amount on the form of high quality that can meet future demand. They both need to construct their very own facility — which prices a whole bunch of hundreds of thousands of {dollars} — or depend on contract manufacturing organizations to provide merchandise on their behalf.

“Prices would be the driving issue to adoption and manufacturing prices have prevented them from already getting into provide chains,” Shenderovich mentioned. “The technique of manufacturing for these merchandise will subsequently be essential, and Synonym’s core perception is that on the subject of industrial infrastructure, productization precedes financialization which precedes mass adoption.”

The global contract bio-manufacturing organization market, which venture-backed startups like Planetary and Culture Biosciences are doing, was estimated to be $22.2 billion in 2021 and is predicted to greater than double by 2030.

Lachter mentioned what Planetary is doing is “certainly making an attempt to shut the capability hole in fermentation,” however the place Synonym varies is its strategy to “focusing extra on productization and financialization of services fairly than a extra conventional CMO mannequin.”

The corporate continues to be very a lot within the early phases, with the co-founders saying their most essential milestone was the launch of the event of its first facility that features web site choice and preliminary design. They anticipate to interrupt floor on the ability within the third quarter of 2023.

This can be adopted up in coming months by additional bulletins on development, structure and different improvement companions.

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